The breast is the most frequent cancer site in the Slovene female population. In the year 2000 there were 932 new breast cancer cases registered (91.2/100,000), the incidence is expected to increase ...in the next ten years. The percentage of cases diagnosed with localized disease is increasing very slowly, in the year 2000 it was less than 50%. Despite the increasing survival(72% relative survival of patients diagnosed in the years 1993-97), breast cancer is the leading cause of cancer-related death in females. Besidesage and sex, the established breast cancer risk factors include certainbenign breast diseases, family history, ionizing radiation, some reproductive factors and obesity. For many other risk factors it is not clear whether the associations are really causal. Primary prevention includes general recommendations for healthy life style, e.g. avoidance of obesity, diet, physical activity and moderate alcohol consumption. Regular screening ofwomen over 50 by mammography with or without clinical examination should reduce mortality by about 35%. While population screening is generally recommended for women aged 50 and over, there is no general agreement on screening in women aged 40-50 years. Breast cancer control could be achieved only by combined efforts aimed at primary prevention and early detection as well as by improving the availability of effective treatment, and by making investments where they prove most cost-effective.
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