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  • New serious safety warnings for targeted anticancer agents after their initial FDA approval [Elektronski vir]
    Stefanovski, Dimitar ...
    Knowledge about the tolerability of targeted anticancer agents can improve after their regulatory approval. In this study, we analyzed the emergence of new serious safety warnings in the updated drug ... labels of targeted anticancer agents that were marketed for at least 10 years. Additionally, possible predictors for their emergence were studied. We found that new serious safety warnings have continued to emerge several years after the initial approval of the targeted anticancer agents, especially small-molecule targeted agents. This research highlights a need for ongoing safety monitoring of targeted anticancer agents. Oncologists, regulators, and payers should be aware of the changing risk–benefit ratios of approved targeted anticancer agents.
    Source: Cancers [Elektronski vir]. - ISSN 2072-6694 (Vol. 17, no. 4, 2025, str. 584-1-584-10)
    Type of material - e-article ; adult, serious
    Publish date - 2025
    Language - english
    COBISS.SI-ID - 226538499