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Vloga molekularnih metod pri diagnostiki sifilisa [Elektronski vir] = The role of molecular methods in the diagnosis of syphilisTriglav, Tina ...Sifilis je kronična bolezen z raznolikimi kliničnimi slikami, povzroča pa jo Treponema pallidum subspecies pallidum. Večinoma se prenaša s tveganim spolnim stikom, možen je prenos z nosečnice na plod ... prek posteljice. Diagnostika sifilisa je odvisna od kliničnih znakov in stadija bolezni, vključuje pa posredne in neposredne metode. Poglavitno vlogo v vseh stadijih bolezni ima še vedno posredna diagnostika sifilisa, ki se uporablja za potrjevanje verjetnih aktivnih okužb, za presejalno testiranje in spremljanje poteka zdravljenja. Za potrjevanje verjetne aktivne okužbe s T. pallidum je potrebno določiti prisotnost tako netreponemskih kot treponemskih protiteles. Neposredne metode za dokazovanje sifilisa vključujejo mikroskopijo v temnem polju, neposredne imunofluorescenčne teste za dokaz antigenov T. pallidum in molekularne metode za dokaz DNK T. pallidum. Molekularne metode, ki tarčno dokazujejo specifične gene T. pallidum, so pomembne zlasti v zgodnji fazi okužbe, hkrati imajo dopolnilno vlogo pri diagnostiki kongenitalnega sifilisa in nevrosifilisa. V prispevku povzemamo različne metode dokazovanja okužbe s T. pallidum, s poudarkom na uporabnosti molekularnih metod.Type of material - conference contribution ; adult, seriousPublish date - 2025Language - slovenianCOBISS.SI-ID - 241652227
Author
Triglav, Tina |
Špik, Vesna, 1976- |
Strašek Smrdel, Katja |
Celar Šturm, Andraž |
Kouter, Katarina, 1989-
Topics
Treponema pallidum |
sifilis |
diagnostika |
laboratorijski testi |
molekularne metode |
Treponema pallidum |
syphilis |
syphilis |
diagnostics |
laboratory tests |
molecular methods
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| Year | Impact factor | Edition | Category | Classification | ||||
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DRS, in which the journal is indexed
| Database name | Field | Year |
|---|
| Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
|---|---|
| Triglav, Tina | 54478 |
| Špik, Vesna, 1976- | 25990 |
| Strašek Smrdel, Katja | 25989 |
| Celar Šturm, Andraž |  |
| Kouter, Katarina, 1989- | 38237 |
Source: Personal bibliographies
and: SICRIS
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