ALL libraries (COBIB.SI union bibliographic/catalogue database)
13.
Comparison of paired cervical scrape and tumor tissue samples for detection of human papillomaviruses in patients with cervical cancer
Jančar, Nina, medicina ...
Purpose of im'estigation: To compare the detection and distribution of HPV genotypes in paired cervical scrape samples and tumor tissue samples in patients with cervical cancer. Methods: Forty ...cervical scrape samples and 40 paired archival or fresh frozen tissue sample s were collected from women withcervicaJ cancer. Polymerase chain reaction with GP5+ and GP6+ primers was performed in all sampJes for HPV DKA detection. All GP5+/GP6+ negative sampleswere additionally tested using INNO-LiPA HPV Genotyping Extra Test. Results: Overall, 39/40 (97.5%) of CC samples were HPV DNA positive. HPV 16 was found in 24/40 samples, HPV 18 in 5/40 samples. A co-infection with two different HPV genotypes was identified in one cervical scrape speci men, whilein tissue samples only single infections were detected. Overall agreementbetween paired samples was 98.75%. Conc/usion: The present study has shown that cervical scrape samples are equally useful for HPV genotype determination as tumor tissue samples in patients with cervical cancer. They can be used as accurate clinical sampJes for detection of HPV genotype causingcervi cal cancer or for epidemiological molecular studies.
It was not necessary to add the material to the shelf.
Bibliographic material was successfully added on shelf.
Adding bibliographical material on shelf was not successful.
Material is already on the shelf.
Permalink
URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year
Impact factor
Edition
Category
Classification
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Impact factor
Select the library membership card:
DRS,
in which the journal is indexed
Database name
Field
Year
Links to authors' personal bibliographies
Links to information on researchers in the SICRIS system
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
