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Pomen merjenja kostne gostote pri bolnikih s kronično ledvično boleznijo = Significance of measuring bone mineral density in patients with chronic kidney diseasePečovnik-Balon, Breda ; Rajšp, Primož ; Soršak, Andrej, ok. 1987-Izhodišča: Pri bolnikih s kronično ledvično boleznijo (KLB) pogosto pride do spremenjenega kostnega metabolizma, znižane mineralne kostne gostote (MKG) in zlomov. Namen raziskave je bil oceniti MKG ... pri bolnikih zdravljenih s hemodializo (HD), kako se MKG spreminja s časom (deltaMKG) in opredeliti dejavnike, povezane s tem. Metode: V prospektivno klinično študijo je bilo vključenih 47 bolnikov zdravljenih s HD. S pomočjo denzitometra Explorer smo izmerili MKG v predelu vratu leve stegnenice (VS), celotnega kolka (CK) in ledvene hrbtenice (LH) in ponovili merjenje po povprečno 20,9 +/- 4,5 mesecih. Rezultati: T-vrednosti MKG manjše kot -1 SD po predelih VS, CK, LH je imelo 67%, 64% in 50% bolnikov. T-vrednosti MKG nižje od -2,5 SD je imelo v istih predelih 27%, 16% oz. 22% bolnikov. Ugotovljena je bila pozitivna korelacija med MKG v predelu LH in težo bolnikov (p=0,009) in negativna korelacija med starostjo bolnikov in MKG v predelu VS (p=0,017). Povprečne vrednosti intaktnega parathormona (iPTH) so pozitivno korelirale z deltaMKG v predelu LH (Rho=0,36; p=0,015), kot tudi v predelu CK (Rho=0,49; p=0,001). Ugotovili smo značilno poslabšanje MKG v predelu LH pri skupini bolnikov z iPTH < 100 pg/ml. Zaključki: MKG v predelu VS in CK je bila nižja kot v predelu LH. Starost in teža sta bila napovednika MKG. Znižanje MKG je bilo največje pri bolnikih z iPTH <100 pg/ml.Source: Novosti v osteologiji : monografija III. Osteoloških dnevov z mednarodno udeležbo, 21. in 22. oktober 2011, Medicinska fakulteta Univerze v Mariboru (Str. 119-127)Type of material - conference contribution ; adult, seriousPublish date - 2011Language - slovenianCOBISS.SI-ID - 4070207
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| Database name | Field | Year |
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| Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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| Pečovnik-Balon, Breda | 15749 |
| Rajšp, Primož | ![]() |
| Soršak, Andrej, ok. 1987- | ![]() |
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