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  • Novi heterociklični acildipeptidi, postopki za njihovo pripravo in farmacevtski pripravki, ki jih vsebujejo = Novel heterocyclic acyldipeptides, process for the preparation thereof and pharmaceutical compositions containing the same : patent št. 9300212 : patent je podeljen z odločbo št. 304-60/93-212-bs-4 z dne 11.01.1995
    Kikelj, Danijel ...
    Novel heterocyclic acyldipeptides of formula (I) wherein Z represents an oxygen or sulphur atom or a-CH2-group; R1 represents hydrogen, a stright or branched chain 1-4C alkyl, cycloalkyl, cycloalkyl, ... trifluoromethyl or benzyl group; R2 represents hydrogen, a straight or branched chain 1-4C alkyl, cycloalkyl, dialkylaminoalkyl, acylaminoalkyl or benzyl group; R3 presents hydrogen, a straight or branched chain 1-12C alkyl or trifluoromethyl group; R4 and R5, which are identical or different, represent an OR6 or NHR6 group, wherein R6 is hydrogen, a stright or branched chain 1-18C alkyl or benzyl group; Y represents a CH2-, =CH- or =N-group; a REPRESENTS A -(CH2)2-group when Y is CH2-, the two rings being trans-condensed, or a (a) od (b) group, wherein R7 represents H, F, Br, Cl, a stright or branched chain 1-4C alkyl, 1-4C alkoxy, trifluormethyl, nitro, amino, alkylamino ot dialkymino group, when Y is =CH-or =N-; are prepared by reacting the corresponding heterocyclic carboxilic acid with the corresponding dipeptides using common regents for theformation of the peptide bond. The heterocyclicacyldipeptides of formula (I) and their pharmaceutically acceptable salts are usel as active compounds in medicaments having immunostimulatory and antitumor activity.
    Vrsta gradiva - patent
    Založništvo in izdelava - Ljubljana : Urad RS za intelektualno lastnino, 1995
    Jezik - slovenski
    COBISS.SI-ID - 139889

Nobena knjižnica v sistemu COBISS.SI nima izvoda tega gradiva.
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