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  • Vitreous levels of interleukin-8 in patients with proliferative diabetic retinopathy
    Globočnik Petrovič, Mojca ...
    Purpose: To determine the levels of interleukin 8 (IL-8) in the vitreous of patients with proliferative diabetic retinopathy (PDR). Design: Observational case-control study. Methods: Vitreous fluid ... samples were obtained by vitreoretinal surgery from 71 eyes of patients with diabetes mellitus type 2 with PDR and from 17 eyes of nondiabetic patients with a macular hole. PDR wasclassified as active and inactive and subdivided according to the extent oflarge-vessel gliotic obliteration. The cytokine levels were measured by cytometric bead array method. Results: The vitreous levels of IL-8 were significantly higher in patients with PDR in comparison with the control subjects (P < .001) and in patients with higher extent of large vessel glioticobliteration (P < .001). A vitreous level of IL-8 was not associated with the presence of active PDR. Conclusion: Increased levels of IL-8 in PDR were associated with a higher extent of large-vessel gliotic obliteration.
    Vir: American journal of ophthalmology. - ISSN 0002-9394 (Letn. 143, št. 1, 2007, str. 175-176)
    Vrsta gradiva - članek, sestavni del
    Leto - 2007
    Jezik - angleški
    COBISS.SI-ID - 22636761

vir: American journal of ophthalmology. - ISSN 0002-9394 (Letn. 143, št. 1, 2007, str. 175-176)
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