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  • Neurohormonal activation and inflammation in c hronic cardiopulmonary disease: a brief systematic review
    Doehner, Wolfram ...
    Chronic cardiopulmonary disease typically induces and maintains (over)activation of several phylogenetically old adaptational and defensive mechanisms. Activation was usually needed for a limited ... period during acute danger or injury. In chronic disease conditions, however, those mechanisms arekept activated for longer periods. Eventually, irreversible damage is done and this contributes to impaired function and worse prognosis in a variety of chronic disease. Landmark trials in chronic heart failure have provided robustevidence for prognostic benefit for neurohormonal antagonists. Retrospective and epidemiological data for their beneficial effect in chronic obstructive pulmonary disease begin to accumulate and new fields (e.g. cancer and stroke) could be pending in the future.
    Vir: Wiener Klinische Wochenschrift. - ISSN 0043-5325 (Jg. 121, hft. 9-10, 2009, str. 293-296)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - angleški
    COBISS.SI-ID - 25697241
    DOI

vir: Wiener Klinische Wochenschrift. - ISSN 0043-5325 (Jg. 121, hft. 9-10, 2009, str. 293-296)
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