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  • Metabolic health in the Slovenian national cohort of kidney transplant patients
    Mlinšek, Gregor ...
    Introduction: Metabolic health refers to the proper functioning and balance of metabolic processes in our bodies. The metabolism of carbohydrates, lipids, and proteins has a direct impact on the ... cardiovascular system. Recent advances in pharmacotherapy have introduced several drugs into clinical practice that can improve cardiometabolic health. Materials and methods: Between September 2023 and March 2024, we systematically collected cardiometabolic data from 800 kidney transplant patients (KTPs) during their routine outpatient visits. These included clinical data – office blood pressure, body weight and height, body mass index (BMI), and waist circumference (WC) – and laboratory data such as high-sensitivity C-reactive protein (hs-CRP), lipid profile, lipoprotein(a) (Lp(a)), glycated hemoglobin (HbA1c), serum urate, serum albumin, and proteinuria from spot urine samples. Patients who required treatment adjustment were selected. Results: Deviations from the desired values of individual components of the metabolic syndrome (blood pressure, WC, triglycerides, high-density lipoprotein cholesterol, and fasting glucose) were observed in 23 – 61.5% of patients. Elevated hs-CRP levels (5 – 10 mg/L), a known cardiovascular risk factor, were observed in 13.5% of patients. Lp(a) levels exceeded the upper normal limit (> 500 mg/L) in 17% of patients. Only a small proportion of patients with moderate to advanced kidney disease – 13% and 23.6%, respectively – had low-density lipoprotein cholesterol levels within the reference range. Conclusions: Between 23% and 61.5% of patients failed to meet target values for individual components of metabolic health. The largest deviation (61.5%) was observed in WC among women. WC and waist-to-height ratio are two simple and reliable parameters for assessing metabolic status.
    Vir: Clinical nephrology. - ISSN 0301-0430 (Vol. 104, supplement 1, str. S1-S9)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2025
    Jezik - angleški
    COBISS.SI-ID - 260328451
    DOI

vir: Clinical nephrology. - ISSN 0301-0430 (Vol. 104, supplement 1, str. S1-S9)
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