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On the role of membrane anisotropy and BAR proteins in the stability of tubular membrane structuresKabaso, Doron ...Recent studies have demonstrated that actin filaments are not crucial for the short-term stability of tubular membrane protrusions originating from the cellsurface. It has also been demonstrated that ... promini nanodomains and curvature inducing I-BAR proteins could account for the stability of the membrane protrusion. Here we constructed an axisymmetric model of a membrane protrusion that excludes actin filaments in order to investigate the contributions of prominin nanodomains (rafts) and I-BAR proteins to the membrane protrusion stability. It was demonstrated that prominin nanodomains and I-BAR proteins can stabilize the membrane protrusion only over a specific range of spontaneous curvature. On the other hand, high spontaneous curvature and/or high density of I-BAR proteins could lead to system instability and to non-uniform contraction in the radial direction of the membrane protrusion. Inagreement with previous studies, it was also shown that the isotropic bending energy of lipids is not sufficient to explain the stability of the observed tubular membrane protrusion without actin filaments.Vir: Journal of biomechanics. - ISSN 0021-9290 (Vol. 45, issue 2, 2012, str. 231-238)Vrsta gradiva - članek, sestavni delLeto - 2012Jezik - angleškiCOBISS.SI-ID - 29065945
Avtor
Kabaso, Doron |
Bobrovska, Nataliya |
Góźdź, Wojciech |
Gov, Nir S. |
Kralj-Iglič, Veronika |
Veranič, Peter |
Iglič, Aleš, 1960-
Teme
Biophysics |
Membranes, Artificial |
Microchemistry |
Anisotropy |
Membrane Proteins |
Actins |
Microtubules |
Mikrokemija |
Membranske beljakovine |
Anizotropija |
Biofizika |
Membrane umetne |
Mikrotubuli |
Aktini
Vnos na polico
Trajna povezava
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| JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP | |
Faktor vpliva
Baze podatkov, v katerih je revija indeksirana
| Ime baze podatkov | Področje | Leto |
|---|
| Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
|---|---|
| Kabaso, Doron | 33030 |
| Bobrovska, Nataliya | ![]() |
| Góźdź, Wojciech | ![]() |
| Gov, Nir S. | ![]() |
| Kralj-Iglič, Veronika | 05916 |
| Veranič, Peter | 08279 |
| Iglič, Aleš, 1960- | 04634 |
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