VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Process for the preparation of O-desmethylvenlafaxine salts : EP20080009046, filling date 14.05.2009 : Appl. no. WO2009138234 (A1) : Applicant: Krka, Tovarna zdravil, d.d. Novo Mesto
    Zupančič, Silvo, 1965- ...
    The present invention relates to a process for the preparation of a salt of O-desmethylvenlafaxine comprising a) dissolving or suspending O-desmethylvenlafaxine in the form of its base in a liquid ... medium selected from the group of solvents and suspending agents,- b) contacting O-desmethylvenlafaxine with a pharmaceutically acceptable acid to form a pharmaceutically acceptable salt of O-desmethylvenlafaxine wherein the pharmaceutically acceptable acid is selected from the group consisting of HCl,HBr, H2SO4, H3PO4, acetic acid, adipic acid, galactaric acid, D-gluconic acid, glutamic acid, glutaric acid, glycolic acid, hippuric acid, lactic acid,oxalic acid, methanesulphonic acid, ethanesulphonic acid, p- toluenesulphonic acid, camphorsulphonic acid, benzenesulphonic acid, malonic acid, L-ascorbic acid, naphtalene-2-sulfonic acid and benzoic acid; and c) separating the pharmaceutically acceptable salt of 0- desmethylvenlaf axine from the liquid medium to recover the salt, and to pharmaceutical formulations containing these salts.
    Vrsta gradiva - patentna prijava
    Založništvo in izdelava - Munich : European Patent Office, 2009
    Jezik - angleški
    COBISS.SI-ID - 2977393

    Povezava(-e):

    http://v3.espacenet.com/publicationDetails/biblio?CC=WO&NR=2009138234A1&KC=A1&FT=D&date=20091119&DB=EPODOC&locale=en_EP

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