VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Computational exploration of the E. Coli MurD enzyme and in silico design of novel inhibitors
    Perdih, Andrej, farmacevt ...
    The increasing incidence of bacterial resistance to the available antibiotics renders the discovery of novel antibacterials urgent. An essential bacterial component, peptidoglycan, is traditionally ... an optimal target with respect to selective toxicity. In the peptidoglycan biosynthetic pathway Mur Iigases catalyze the intracellular construction of its peptide moiety. MurD enzyme in particular catalyses an incorporation of the D-Glu into the UMA precursor coupled with the concurrent ATP hydrolysis.
    Vir: 16th SCI/RSC Medicinal Chemistry Symposium : Sunday 11-Wednesday 14 September 2011, Churchill College, Cambridge, UK (Str. P-16)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2011
    Jezik - angleški
    COBISS.SI-ID - 4784666

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